All Angles Creatures

FGF10 mutant Gallipato

This is an inherited trait, not a morph. Nobody breeds for it.

peer reviewed

Suzuki et al. (2024) "established Fgf10 mutant lines [using CRISPR-Cas9] in the newt  Pleurodeles waltl which has amazing regenerative ability. While Fgf10 mutant forelimbs develop normally, the hindlimbs fail to develop and downregulate FGF target genes. Despite these developmental defects, Fgf10 mutants were able to regenerate normal hindlimbs rather than recapitulating the embryonic phenotype. Together, our results demonstrate an important role for FGF10 in hindlimb formation, but little or no function in regeneration ... ." This study involves genetically modified organisms (GM

Offspring odds

No numbers for this one.

No inheritance mode has been recorded for FGF10 mutant, so no offspring odds are given. Guessing one would be worse than saying nothing: a breeder would plan a season on it.

What this rests on

A peer-reviewed paper identifies the variant behind this morph.

  • Fgf10 mutant newts regenerate normal hindlimbs despite severe developmental defects.Proc Natl Acad Sci U S A 2024

Entry in Online Mendelian Inheritance in Animals